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Reality TV personality Anna ?°Chickadee?± Cardwell?awho made an appearance on TLC?ˉs ?°Here Comes Honey Boo Boo?±?adied Sunday, based on an Instagram publish shared by her mother, June Shannon.

?°With the breaking heart, we’re announcing that @annamarie35 is not around,?± Shannon shared on Instagram. ?°She died within my home yesterday peacefully at 11:12 p.m.?±

Cardwell, who had been 29, was identified as having stage 4 adrenal carcinoma in The month of january 2023 after seeking take care of stomachaches.1 Further testing demonstrated the cancer had spread to her liver, kidney, and lung. She started chemotherapy in March?amonths later, in May, Cardwell shared on Instagram that they was on her behalf third round of chemotherapy which things were ?°looking good.?±

However, it appears her condition rapidly deteriorated. Within an Instagram publish shared 2 days before Cardwell?ˉs dying, Shannon shared a plea together with her Instagram supporters to help keep her family within their ideas.

Cardwell is survived by her two kids, Kaitlyn and Kylee, in addition to her mother and half-siblings Alanna ?°Honey Boo Boo?± Thompson, Lauryn ?°Pumpkin?± Efird, and Jessica ?°Chubbs?± Shannon.

What’s Adrenal Cancer?

Adrenal cancers are extremely rare?athough the precise figures are unknown, it?ˉs believed that just about 200 cases are diagnosed every year.2

Though adrenal cancers (carcinomas) can happen in people of all ages, the typical age at diagnosis is all about 46 years of age.2

Adrenal cancer begins within the adrenal glands?asmall glands that sit over the kidneys.

?°The adrenal [glands] have the effect of producing hormones that regulate various bodily processes, including metabolic process, bloodstream pressure, and stress response,?± Kedar Kirtane, MD, a helper member within the department of mind and neck-endocrine oncology and medical director for Solid Tumor Cellular Therapy at Moffitt Cancer Center, told Health.

Tumors most frequently develop within the cortex from the adrenal gland?athe two primary types are adenomas (benign or non-cancerous tumors) and carcinomas (malignant or cancerous tumors). The particular kind of cancer that develops within the cortex from the adrenal gland is known as adrenal cortical carcinoma.3

What Can Cause Adrenal Cancer?

It?ˉs presently unknown what can cause adrenal cancer, meaning it?ˉs also difficult to avoid the condition. Certain lifestyle risk factors?alike getting weight problems, as being a smoker, or living an inactive lifestyle?ahave been connected by having an elevated chance of other kinds of cancer, but information is missing on their own link with adrenal cancer.4

However, ?°there really are a couple of rare inherited cancer syndromes that will place you at elevated chance of developing adrenal cancer,?± stated Melanie Goldfarb, MD, endocrine surgeon and director from the Center for Endocrine Tumors and Disorders at Saint John?ˉs Cancer Institute at Providence Saint John’s Health Center.

Individuals rare genetic syndromes include Li-Fraumeni syndrome, Beckwith-Wiedemann syndrome, multiple endocrine neoplasia (MEN1), familial adenomatous polyposis (FAP), and Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC).4

Do you know the Signs and symptoms of Adrenal Cancer?

Signs and symptoms of adrenal cancer vary?asome may result from hormones produced by the tumor, while some can happen since the tumor has become so large it presses on other organs.

?°These tumors could possibly get quite large?asome are how big a cantaloupe when they?ˉre diagnosed,?± Amanda M. Laird, MD, chief within the Portion of Endocrine Surgery in the Rutgers Cancer Institute, told Health. ?°Because of the positioning, the tumors could possibly get pretty big before people become symptomatic.?±

When an adrenal melanoma grows too big, you can get the next signs and symptoms:

A lump within the abdomen

Abdominal or back discomfort

A complete perspective of abdomen

When an adrenal melanoma makes an excessive amount of a particular hormone?acortisol, aldosterone, testosterone, or estrogen?athe signs and symptoms rely on which hormone is affected, and whether it?ˉs causing that hormone to improve that face men or females.5

Signs and symptoms of an excessive amount of cortisol:

Putting on weight hard, neck, and trunk of body thin legs and arms

Development of fine hair evidently, shoulders, or arms

A round, red, full face

A lump of fat on the rear of the neck

A deepening from the voice swelling of reproductive organs

Muscle weakness

High bloodstream sugar

High bloodstream pressure

Signs and symptoms of an excessive amount of aldosterone:

High bloodstream pressure

Muscle weakness, cramps

Frequent peeing

Feeling thirsty

Signs and symptoms of an excessive amount of testosterone in ladies:

Development of fine hair evidently, shoulders, or arms



A deepening from the voice

Insufficient the monthly period

Signs and symptoms of an excessive amount of oestrogen in ladies:

Irregular periods

Vaginal bleeding after menopause

Putting on weight

Signs and symptoms of an excessive amount of oestrogen that face men:

Development of breast growth

Lower libido


How’s Adrenal Cancer Diagnosed and Treated?

Adrenal cancer is most frequently found accidentally through imaging tests accomplished for one more reason, or because of hormone signs and symptoms or signs and symptoms because of the tumor growing too big.

Associated with pension transfer cancers, early recognition is essential which are more favorable outcomes. ?°Patients which do well are the type that people identify incidentally?ameaning someone had imaging scans for an additional reason, we found full of around the adrenal gland, so we required it,?± stated Goldfarb.

That early treatment may include surgically taking out the tumor or even the entire affected adrenal gland, based on John Lane, MD, PhD, director of urologic oncology at Corewell Health.

If, in later stages, there?ˉs cancer left after surgical procedures or cancer has spread with other areas of the body, chemotherapy or radiation can be utilized, though it?ˉs ?°often not so effective,?± stated Lane.

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